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Fioricet is a combination medication that is used to treat complex tension headaches when other medications have not been effective.

Fioricet is a combination medication used to treat migraines or severe headaches. Learn the uses, effects and how to use Fioricet safely.

Fioricet (butalbital / acetaminophen / caffeine) works better and faster in treating tension headaches than the combination of acetaminophen and codeine.
Fioricet (butalbital / acetaminophen / caffeine) has a cheaper, generic version.
Fioricet (butalbital / acetaminophen / caffeine) does not require dosage adjustments if you have kidney and liver problems.

What is Fioricet?

Fioricet is the brand name multi-ingredient medication that’s used to treat some types of headaches. It’s also available in generic form.
Fioricet contains:

butalbital 50mg
acetaminophen 300mg
caffeine 40mg

It’s FDA-approved to treat symptoms of a common type of headache known as tension headache but is also prescribed off-label for migraine.

Butalbital APAP Caffeine is used to treat tension headaches. Acetaminophen helps to decrease the pain from the headache. Caffeine helps increase the effects of acetaminophen. Butalbital is a sedative that helps to decrease anxiety and cause sleepiness and relaxation.

Butalbital APAP Caffeine has following side effects: Bloated or “gassy” feeling, dizziness or lightheadedness (mild), drowsiness (mild), nausea, vomiting, or stomach pain (occurring without other symptoms of overdose), Bleeding or crusting sores on lips, chest pain, fever with or without chills, hive-like swellings (large) on eyelids, face, lips, and/or tongue, muscle cramps or pain

Butalbital APAP Caffeine can not be taken for a long time, your body may get used to it so that larger amounts are needed to produce the same effects. This is called tolerance to the medicine. Also, butalbital may become habit-forming (causing mental or physical dependence) when it is used for a long time or in large doses. Physical dependence may lead to withdrawal side effects when you stop taking the medicine. In patients who get headaches, the first symptom of withdrawal may be new (rebound) headaches.

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Butalbital, acetaminophen, and caffeine combination is used to relieve symptoms of tension (or muscle contraction) headaches.

Butalbital belongs to the group of medicines called barbiturates. Barbiturates act in the central nervous system (CNS) to produce their effects.

Acetaminophen is used to relieve pain and reduce fever in patients. It does not become habit-forming when taken for a long time. But acetaminophen may cause other unwanted effects when taken in large doses, including liver damage.

When butalbital is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.

Caffeine is a CNS stimulant that is used with pain relievers to increase their effect. It has also been used for migraine headaches. However, caffeine can also cause physical dependence when it is used for a long time. This may lead to withdrawal (rebound) headaches when you stop taking it.

This medicine is available only with your doctor’s prescription.

This product is available in the following dosage forms:

Tablet
Capsule
Solution

What should you know before you take Fioricet ?

Before taking Fioricet, tell your doctor or pharmacist if you are allergic to acetaminophen, caffeine, or butalbital; or to other barbiturates (such as phenobarbital) or xanthine derivatives (such as theophylline); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe breathing problems (such as bronchopneumonia), a certain enzyme disorder (porphyria), liver disease, kidney disease, personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol), mental/mood disorders, abdominal/stomach problems (such as stomach ulcer).

Do not use Fioricet if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

You should not use Fioricet if you are allergic to acetaminophen, butalbital, or caffeine, if you have porphyria, or if you have recently used alcohol, sedatives, tranquilizers, or other narcotic medications.

To make sure Fioricet is safe for you, tell your doctor if you have:

- liver disease, cirrhosis, a history of alcoholism or drug addiction, or if you drink more than 3 alcoholic beverages per day;
- kidney disease;
- asthma, sleep apnea, or other breathing disorder;
- stomach ulcer or bleeding;
- a history of skin rash caused by any medication;
- a history of mental illness or suicidal thoughts; or
- if you use medicine to prevent blood clots.

It is not known whether Fioricet will harm an unborn baby. If you use butalbital while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.

This drug may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Avoid alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).

Liquid products may contain alcohol, sugar and/or aspartame. Caution is advised if you have diabetes, alcohol dependence, liver disease, phenylketonuria (PKU), or any other condition that requires you to limit/avoid these substances in your diet. Ask your doctor or pharmacist about using this product safely.

Before having surgery or certain medical procedures (such as a heart stress test or a procedure to restore a normal heart rhythm if you have an unusually fast heartbeat), tell your doctor or dentist that you use this medication and about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Older adults may be more sensitive to the side effects of this drug, especially drowsiness and trouble falling asleep. These side effects can increase the risk of falling.

During pregnancy, this medication should be used only when clearly needed. Using it for long periods or in high doses near the expected delivery date is not recommended because of possible harm to the unborn baby. Discuss the risks and benefits with your doctor. Infants born to mothers who have used this medication for an extended time may have withdrawal symptoms such as irritability, abnormal/persistent crying, vomiting, seizures, or diarrhea. Tell your doctor right away if you notice any of these symptoms in your newborn.

This drug passes into breast milk and could have undesirable effects on a nursing infant. Consult your doctor before breast-feeding.

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of butalbital, acetaminophen, and caffeine combination in children younger than 12 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of butalbital, acetaminophen, and caffeine combination in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving butalbital, acetaminophen, and caffeine combination.

Pregnancy

Information about this butalbital-acetaminophen-and-caffeine-oral-route
	Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Fioricet Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Riociguat

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Alfentanil
Alprazolam
Amobarbital
Anisindione
Aprobarbital
Butabarbital
Carisoprodol
Chloral Hydrate
Chlordiazepoxide
Chlorzoxazone
Clarithromycin
Clonazepam
Clorazepate
Dantrolene
Darunavir
Diazepam
Dicumarol
Doxorubicin
Doxorubicin Hydrochloride Liposome
Esketamine
Estazolam
Ethchlorvynol
Etonogestrel
Flunitrazepam
Flurazepam
Halazepam
Imatinib
Iobenguane I 131
Isoniazid
Ketazolam
Lorazepam
Lormetazepam
Medazepam
Mephenesin
Mephobarbital
Meprobamate
Metaxalone
Methocarbamol
Methohexital
Midazolam
Nifedipine
Nitrazepam
Oxazepam
Peginterferon Alfa-2b
Pentobarbital
Phenindione
Phenobarbital
Phenprocoumon
Piperaquine
Pixantrone
Pneumococcal 13-Valent Vaccine, Diphtheria Conjugate
Prazepam
Primidone
Quazepam
Secobarbital
Sodium Oxybate
Temazepam
Thiopental
Triazolam
Ulipristal

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Acenocoumarol
Cannabis
Carbamazepine
Fosphenytoin
Lixisenatide
Ospemifene
Phenytoin
Prednisone
Warfarin
Zidovudine

Other Prescription Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Ethanol
Tobacco

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Cabbage
Ethanol

Fioricet Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

1. Lightheadedness
2. shortness of breath

Incidence not known

1. 1. Abdominal or stomach pain
  2. black, tarry stools
  3. bleeding gums
  4. blistering, peeling, or loosening of the skin
  5. blood in the urine or stools
  6. blurred vision
  7. change in the frequency of urination or amount of urine
  8. chills
  9. cough
  10. diarrhea
  11. difficulty with breathing
  12. difficulty with swallowing
  13. dizziness
  14. drowsiness
  15. dry mouth
  16. fainting
  17. fast, pounding, or irregular heartbeat or pulse
  18. flushed or dry skin
  19. fruit-like breath odor
  20. hives, itching, or skin rash
  21. increased hunger
  22. increased thirst
  23. increased urination
  24. joint or muscle pain
  25. loss of appetite
  26. nausea or vomiting
  27. pinpoint red spots on the skin
  28. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  29. red skin lesions, often with a purple center
  30. red, irritated eyes
  31. seizures
  32. shakiness in the legs, arms, hands, or feet
  33. sore throat
  34. sores, ulcers, or white spots in the mouth or on the lips
  35. sweating
  36. swelling of the feet or lower legs
  37. tightness in the chest
  38. trembling or shaking of the hands or feet
  39. troubled breathing
  40. unexplained weight loss
  41. unusual bleeding or bruising
  42. unusual tiredness or weakness
  43. weakness

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

1. 1. Confusion as to time, place, or person
  2. dark urine
  3. difficult or painful urination
  4. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  5. fever
  6. general feeling of discomfort or illness
  7. hallucinations
  8. headache
  9. holding false beliefs that cannot be changed by fact
  10. increased sweating
  11. irregular, fast or slow, or shallow breathing
  12. light-colored stools
  13. loss of appetite
  14. pale or blue lips, fingernails, or skin
  15. restlessness
  16. sudden decrease in the amount of urine
  17. sweating
  18. trouble sleeping
  19. unpleasant breath odor
  20. unusual excitement, nervousness, or restlessness
  21. vomiting of blood
  22. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Relaxed and calm
sleepiness

Incidence not known

1. 1. Anxiety
  2. bloated
  3. constipation
  4. continuing ringing or buzzing or other unexplained noise in the ears
  5. depression
  6. earache
  7. excess air or gas in the stomach or intestines
  8. false or unusual sense of well-being
  9. full feeling
  10. hearing loss
  11. heartburn
  12. heavy eyelids
  13. high energy
  14. hot spells
  15. hyperventilation
  16. irritability
  17. numbness
  18. pain in the leg
  19. passing gas
  20. sluggishness
  21. stuffy nose
  22. tingling sensation

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

We do not suggest you to take Fioricet or Gabapentinfor a long time, you need go to your local health professional to treat your pain without prescription. We think exercising is the best way to relieve your pain. Exercising is a very good methods. Exercising can enhance your immune system and increase your muscle strength and make your nerve strong. You can also take some nutrition from food. You can try Health Foods here to make you more health and young and get rid of your pain.

What should I avoid while taking Fioricet?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Avoid drinking alcohol. It may increase your risk of liver damage while taking acetaminophen.

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

While you are taking this medication, avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor’s advice.

Is Fioricet Addictive?

Although it’s only a prescription headache medication, Fioricet has the potential to cause addiction. If a person follows their prescription guidelines and uses the medication correctly, the risks of addiction are low. However, if someone takes too much Fioricet, they may develop tolerance to its effects. A person with tolerance to a certain dose of Fioricet will require higher doses of the medication to alleviate their headaches.

When a person with tolerance starts to take more Fioricet, possibly by obtaining more prescriptions, they may eventually become dependent on it. In other words, they may feel unable to get through the day without taking Fioricet; if they stop, they will experience symptoms of withdrawal. These symptoms arise because their body has grown accustomed to Fioricet in high doses.

If a Fioricet-dependent person attempts to weather withdrawal alone, it’s likely they will take Fioricet again just to relieve the symptoms of withdrawal. This is a hallmark characteristic of addiction. Anyone who compulsively abuses Fioricet to avoid withdrawal likely has an addiction to Fioricet. Additionally, people with an addiction to Fioricet will experience cravings for the medication which further compel them to keeping using it.

Moreover, the ingredient Butalbital is an addictive substance in its own right. Butalbital can cause someone to get “high” because it’s a Central Nervous System (CNS) Depressant. Since Butalbital is part of Fioricet, it is possible for someone to abuse Fioricet as a recreational drug. At high doses, Fioricet can intoxicate a person in a manner similar to alcohol. People who abuse Fioricet for this purpose have as much of a risk of developing an addiction as they would have if they repeatedly used an illegal drug.

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What is Fioricet?

What should you know before you take Fioricet ?

Allergies

Pediatric

Geriatric

Pregnancy

Breastfeeding

Fioricet Drug Interactions

Other Prescription Interactions

Other Medical Problems

Fioricet Side Effects

More common

Incidence not known

Symptoms of overdose

More common

Incidence not known

What should I avoid while taking Fioricet?

Is Fioricet Addictive?